PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration
<p>Abstract</p> <p>The normal function of poly (ADP-ribose) polymerase-1 (PARP-1) is the routine repair of DNA damage by adding poly (ADP ribose) polymers in response to a variety of cellular stresses. Recently, it has become widely appreciated that PARP-1 also participates in dive...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-12-01
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Series: | Cell Communication and Signaling |
Online Access: | http://www.biosignaling.com/content/8/1/31 |