Absence of the primary cilia formation gene Talpid3 impairs muscle stem cell function

Absence of the primary cilia formation gene Talpid3 impairs muscle stem cell function

Abstract Skeletal muscle stem cells (MuSC) are crucial for tissue homoeostasis and repair after injury. Following activation, they proliferate to generate differentiating myoblasts. A proportion of cells self-renew, re-enter the MuSC niche under the basal lamina outside the myofiber and become quies...

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Bibliographic Details
Main Authors: Victor Martinez-Heredia, Danielle Blackwell, Sujith Sebastian, Timothy Pearson, Gi Fay Mok, Laura Mincarelli, Charlotte Utting, Leighton Folkes, Ernst Poeschl, Iain Macaulay, Ulrike Mayer, Andrea Münsterberg
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05503-9

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https://doi.org/10.1038/s42003-023-05503-9

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