The role of histone methylase and demethylase in antitumor immunity: A new direction for immunotherapy

Epigenetic modifications may alter the proliferation and differentiation of normal cells, leading to malignant transformation. They can also affect normal stimulation, activation, and abnormal function of immune cells in the tissue microenvironment. Histone methylation, coordinated by histone methyl...

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Bibliographic Details
Main Authors: Yuanling Zhang, Junhao Chen, Hang Liu, Rui Mi, Rui Huang, Xian Li, Fei Fan, Xueqing Xie, Jie Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1099892/full