Rational Design of Adenylate Kinase Thermostability through Coevolution and Sequence Divergence Analysis

Protein engineering is actively pursued in industrial and laboratory settings for high thermostability. Among the many protein engineering methods, rational design by bioinformatics provides theoretical guidance without time-consuming experimental screenings. However, most rational design methods ei...

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Bibliographic Details
Main Authors: Jian Chang, Chengxin Zhang, Huaqiang Cheng, Yan-Wen Tan
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/5/2768