Dynamics of Low-Level Viremia and Immune Activation after Switching to a Darunavir-Based Regimen

Dynamics of Low-Level Viremia and Immune Activation after Switching to a Darunavir-Based Regimen

There is an ongoing debate regarding whether low-level viremia (LLV), in particular persistent LLV, during HIV treatment with optimal adherence originates from low-level viral replication, viral production, or both. We performed an observational study in 30 individuals with LLV who switched to a boo...

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Bibliographic Details
Main Authors: Arjen J. Stam, Ninée V. E. J. Buchholtz, Wouter F. W. Bierman, Reinout van Crevel, Andy I. M. Hoepelman, Mark A. A. Claassen, Heidi S. M. Ammerlaan, Berend J. van Welzen, Marjo E. E. van Kasteren, Steven F. L. van Lelyveld, Dorien de Jong, Kiki Tesselaar, Matthijs van Luin, Monique Nijhuis, Annemarie M. J. Wensing, LOWERIT Study Team
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Viruses
Subjects:
HIV-1
low-level viremia
immune activation
HIV pathogenesis
replication
production
Online Access:https://www.mdpi.com/1999-4915/16/2/182

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https://www.mdpi.com/1999-4915/16/2/182

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