Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch

The structure of mismatched DNA-Polζ ternary complex provides a basis for understanding what makes Polζ adept at extending DNA synthesis past mismatched base pairs.

Bibliografiska uppgifter
Huvudupphovsmän: Radhika Malik, Robert E. Johnson, Louise Prakash, Satya Prakash, Iban Ubarretxena-Belandia, Aneel K. Aggarwal
Materialtyp: Artikel
Språk:English
Publicerad: Nature Portfolio 2022-02-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-022-28644-7