Simulation of pharmacokinetic drug-drug interaction and dosage regimens optimization of nelfinavir and cepharanthine as a potential combination against COVID-19

The pharmacokinetic (PK) drug-drug interactions (DDIs) of nelfinavir and cepharanthine combination is limited information in human. In addition, the dosage regimen of this combination is not available for COVID-19 treatment. The objective of this study was to perform in silico simulations using Gast...

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Bibliographic Details
Main Author: Wichit Nosoongnoen
Format: Article
Language:English
Published: Faculty of Pharmacy, Mahidol University 2023-01-01
Series:Pharmaceutical Sciences Asia
Subjects:
Online Access:https://pharmacy.mahidol.ac.th/journal/_files/2023-50-1_2.pdf