PTK6 regulates IGF-1-induced anchorage-independent survival.

PTK6 regulates IGF-1-induced anchorage-independent survival.

Proteins that are required for anchorage-independent survival of tumor cells represent attractive targets for therapeutic intervention since this property is believed to be critical for survival of tumor cells displaced from their natural niches. Anchorage-independent survival is induced by growth f...

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Bibliographic Details
Main Authors: Hanna Y Irie, Yashaswi Shrestha, Laura M Selfors, Fabianne Frye, Naoko Iida, Zhigang Wang, Lihua Zou, Jun Yao, Yiling Lu, Charles B Epstein, Sridaran Natesan, Andrea L Richardson, Kornelia Polyak, Gordon B Mills, William C Hahn, Joan S Brugge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2909213?pdf=render

Internet

http://europepmc.org/articles/PMC2909213?pdf=render

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