Sensitivity of SARS-CoV-2 Life Cycle to IFN Effects and ACE2 Binding Unveiled with a Stochastic Model

Sensitivity of SARS-CoV-2 Life Cycle to IFN Effects and ACE2 Binding Unveiled with a Stochastic Model

Mathematical modelling of infection processes in cells is of fundamental interest. It helps to understand the SARS-CoV-2 dynamics in detail and can be useful to define the vulnerability steps targeted by antiviral treatments. We previously developed a deterministic mathematical model of the SARS-CoV...

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Bibliographic Details
Main Authors: Igor Sazonov, Dmitry Grebennikov, Andreas Meyerhans, Gennady Bocharov
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Viruses
Subjects:
SARS-Cov-2
type I interferon (IFN)
the ACE2 receptor
virus dynamics
mathematical model
stochastic processes
Online Access:https://www.mdpi.com/1999-4915/14/2/403

Internet

https://www.mdpi.com/1999-4915/14/2/403

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