Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice

Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice

Abstract Background Gut microbiota are involved in the onset and development of chronic intestinal inflammation. The recently described endocannabinoidome (eCBome), a diverse and complex system of bioactive lipid mediators, has been reported to play a role in various physio-pathological processes su...

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Bibliographic Details
Main Authors: Tommaso Venneri, Giada Giorgini, Nadine Leblanc, Nicolas Flamand, Francesca Borrelli, Cristoforo Silvestri, Vincenzo Di Marzo
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Lipids in Health and Disease
Subjects:
2,4-dinitrobenzenesulfonic acid (DNBS)
Colitis
Endocannabinoids
Microbiome
Antibiotics
Germ-free mice
Online Access:https://doi.org/10.1186/s12944-023-01823-1

Internet

https://doi.org/10.1186/s12944-023-01823-1

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