Cholera toxin B scaffolded, focused SIV V2 epitope elicits antibodies that influence the risk of SIVmac251 acquisition in macaques

Cholera toxin B scaffolded, focused SIV V2 epitope elicits antibodies that influence the risk of SIVmac251 acquisition in macaques

IntroductionAn efficacious HIV vaccine will need to elicit a complex package of innate, humoral, and cellular immune responses. This complex package of responses to vaccine candidates has been studied and yielded important results, yet it has been a recurring challenge to determine the magnitude and...

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Bibliographic Details
Main Authors: Mohammad Arif Rahman, Manuel Becerra-Flores, Yury Patskovsky, Isabela Silva de Castro, Massimiliano Bissa, Shraddha Basu, Xiaoying Shen, LaTonya D. Williams, Sarkis Sarkis, Kombo F. N’guessan, Celia LaBranche, Georgia D. Tomaras, Pyone Pyone Aye, Ronald Veazey, Dominic Paquin-Proulx, Mangala Rao, Genoveffa Franchini, Timothy Cardozo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
SIV
single epitope subunit vaccine
cholera toxin B scaffold vaccine
DNA/ALVAC vaccine
ADCC
efferocytosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1139402/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1139402/full

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