Inferential Structure Determination of Chromosomes from Single-Cell Hi-C Data.

Chromosome conformation capture (3C) techniques have revealed many fascinating insights into the spatial organization of genomes. 3C methods typically provide information about chromosomal contacts in a large population of cells, which makes it difficult to draw conclusions about the three-dimension...

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Bibliographic Details
Main Authors: Simeon Carstens, Michael Nilges, Michael Habeck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5226817?pdf=render