Inferential Structure Determination of Chromosomes from Single-Cell Hi-C Data.
Chromosome conformation capture (3C) techniques have revealed many fascinating insights into the spatial organization of genomes. 3C methods typically provide information about chromosomal contacts in a large population of cells, which makes it difficult to draw conclusions about the three-dimension...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-12-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5226817?pdf=render |