Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex

Abstract Background Neuropsychiatric disorders afflict a large portion of the global population and constitute a significant source of disability worldwide. Although Genome-wide Association Studies (GWAS) have identified many disorder-associated variants, the underlying regulatory mechanisms linking...

Full description

Bibliographic Details
Main Authors: Shuang Liu, Hyejung Won, Declan Clarke, Nana Matoba, Saniya Khullar, Yudi Mu, Daifeng Wang, Mark Gerstein
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Genome Medicine
Online Access:https://doi.org/10.1186/s13073-022-01133-8