asymptoticMK: A Web-Based Tool for the Asymptotic McDonald–Kreitman Test

The McDonald–Kreitman (MK) test is a widely used method for quantifying the role of positive selection in molecular evolution. One key shortcoming of this test lies in its sensitivity to the presence of slightly deleterious mutations, which can severely bias its estimates. An asymptotic version of t...

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Bibliographic Details
Main Authors: Benjamin C. Haller, Philipp W. Messer
Format: Article
Language:English
Published: Oxford University Press 2017-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.039693