asymptoticMK: A Web-Based Tool for the Asymptotic McDonald–Kreitman Test
The McDonald–Kreitman (MK) test is a widely used method for quantifying the role of positive selection in molecular evolution. One key shortcoming of this test lies in its sensitivity to the presence of slightly deleterious mutations, which can severely bias its estimates. An asymptotic version of t...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2017-05-01
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Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.117.039693 |