Exploring Three Avenues: Chemo- and Regioselective Transformations of 1,2,4-Triketone Analogs into Pyrazoles and Pyridazinones

Exploring Three Avenues: Chemo- and Regioselective Transformations of 1,2,4-Triketone Analogs into Pyrazoles and Pyridazinones

A convenient approach to substituted pyrazoles and pyridazinones based on 1,2,4-triketones is presented. Chemo- and regiocontrol in condensations of <i>t</i>-Bu, Ph-, 2-thienyl-, and CO<sub>2</sub>Et-substituted 1,2,4-triketone analogs with hydrazines are described. The direc...

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Bibliographic Details
Main Authors: Yulia O. Edilova, Ekaterina A. Osipova, Pavel A. Slepukhin, Victor I. Saloutin, Denis N. Bazhin
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
1,2,4-triketone analogs
pyrazole
pyridazine
regioselectivity
chemoselectivity
building blocks
Online Access:https://www.mdpi.com/1422-0067/24/18/14234

Internet

https://www.mdpi.com/1422-0067/24/18/14234

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