Efficacy and Safety of Trazodone and Gabapentin Fixed-Dose Combination in Patients Affected by Painful Diabetic Neuropathy: Randomized, Controlled, Dose-Finding Study

Efficacy and Safety of Trazodone and Gabapentin Fixed-Dose Combination in Patients Affected by Painful Diabetic Neuropathy: Randomized, Controlled, Dose-Finding Study

Abstract Introduction Up to 50% of diabetic patients with neuropathy suffer from chronic pain, namely painful diabetic neuropathy (PDN), an unmet medical need with significant impact on quality of life. Gabapentin is widely used for PDN, albeit with frequent dose-limiting effects. Trazodone, an anti...

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Bibliographic Details
Main Authors: Solomon Tesfaye, Ponnusamy Saravanan, Edvard Ehler, Karel Zinek, Ilona Palka-Kisielowska, Marcin Nastaj, Pierre Serusclat, Paola Lipone, Andrea Vergallo, Elisa Quarchioni, Fabrizio Calisti, Alessandro Comandini, Agnese Cattaneo
Format: Article
Language:English
Published: Adis, Springer Healthcare 2024-06-01
Series:Pain and Therapy
Subjects:
Trazodone
Painful diabetic neuropathy
Online Access:https://doi.org/10.1007/s40122-024-00624-3

Internet

https://doi.org/10.1007/s40122-024-00624-3

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