Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Abstract Background Activated regulatory T cells (aTregs) play a vital role in promoting a tumor immunosuppressive microenvironment in laryngeal squamous cell carcinoma (LSCC). However, the regulatory factors that induce the generation of aTregs are not clear. Herein, we investigated the effect of a...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Hang Li, Ruihua Fang, Renqiang Ma, Yudong Long, Rui He, Huanhuan Lyu, Lin Chen, Yihui Wen
Format: Artykuł
Język:English
Wydane: BMC 2024-10-01
Seria:Head & Face Medicine
Hasła przedmiotowe:
Amphiregulin
Epidermal growth factor receptor
Laryngeal squamous cell carcinoma
Immunosuppressive microenvironment
Regulatory T cells
Dostęp online:https://doi.org/10.1186/s13005-024-00466-6

Internet

https://doi.org/10.1186/s13005-024-00466-6

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