Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Abstract Background Activated regulatory T cells (aTregs) play a vital role in promoting a tumor immunosuppressive microenvironment in laryngeal squamous cell carcinoma (LSCC). However, the regulatory factors that induce the generation of aTregs are not clear. Herein, we investigated the effect of a...

Podrobná bibliografie
Hlavní autoři:	Hang Li, Ruihua Fang, Renqiang Ma, Yudong Long, Rui He, Huanhuan Lyu, Lin Chen, Yihui Wen
Médium:	Článek
Jazyk:	English
Vydáno:	BMC 2024-10-01
Edice:	Head & Face Medicine
Témata:	Amphiregulin Epidermal growth factor receptor Laryngeal squamous cell carcinoma Immunosuppressive microenvironment Regulatory T cells
On-line přístup:	https://doi.org/10.1186/s13005-024-00466-6

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