Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Abstract Background Activated regulatory T cells (aTregs) play a vital role in promoting a tumor immunosuppressive microenvironment in laryngeal squamous cell carcinoma (LSCC). However, the regulatory factors that induce the generation of aTregs are not clear. Herein, we investigated the effect of a...

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Bibliographic Details
Main Authors:	Hang Li, Ruihua Fang, Renqiang Ma, Yudong Long, Rui He, Huanhuan Lyu, Lin Chen, Yihui Wen
Format:	Article
Language:	English
Published:	BMC 2024-10-01
Series:	Head & Face Medicine
Subjects:	Amphiregulin Epidermal growth factor receptor Laryngeal squamous cell carcinoma Immunosuppressive microenvironment Regulatory T cells
Online Access:	https://doi.org/10.1186/s13005-024-00466-6

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