Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Abstract Background Activated regulatory T cells (aTregs) play a vital role in promoting a tumor immunosuppressive microenvironment in laryngeal squamous cell carcinoma (LSCC). However, the regulatory factors that induce the generation of aTregs are not clear. Herein, we investigated the effect of a...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Hang Li, Ruihua Fang, Renqiang Ma, Yudong Long, Rui He, Huanhuan Lyu, Lin Chen, Yihui Wen
Формат:	Өгүүллэг
Хэл сонгох:	English
Хэвлэсэн:	BMC 2024-10-01
Цуврал:	Head & Face Medicine
Нөхцлүүд:	Amphiregulin Epidermal growth factor receptor Laryngeal squamous cell carcinoma Immunosuppressive microenvironment Regulatory T cells
Онлайн хандалт:	https://doi.org/10.1186/s13005-024-00466-6

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