Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Abstract Background Activated regulatory T cells (aTregs) play a vital role in promoting a tumor immunosuppressive microenvironment in laryngeal squamous cell carcinoma (LSCC). However, the regulatory factors that induce the generation of aTregs are not clear. Herein, we investigated the effect of a...

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Detalhes bibliográficos
Main Authors: Hang Li, Ruihua Fang, Renqiang Ma, Yudong Long, Rui He, Huanhuan Lyu, Lin Chen, Yihui Wen
Formato: Artigo
Idioma:English
Publicado em: BMC 2024-10-01
Colecção:Head & Face Medicine
Assuntos:
Amphiregulin
Epidermal growth factor receptor
Laryngeal squamous cell carcinoma
Immunosuppressive microenvironment
Regulatory T cells
Acesso em linha:https://doi.org/10.1186/s13005-024-00466-6

Internet

https://doi.org/10.1186/s13005-024-00466-6

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