Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Amphiregulin promotes activated regulatory T cell-suppressive function via the AREG/EGFR pathway in laryngeal squamous cell carcinoma

Abstract Background Activated regulatory T cells (aTregs) play a vital role in promoting a tumor immunosuppressive microenvironment in laryngeal squamous cell carcinoma (LSCC). However, the regulatory factors that induce the generation of aTregs are not clear. Herein, we investigated the effect of a...

Полное описание

Библиографические подробности
Главные авторы: Hang Li, Ruihua Fang, Renqiang Ma, Yudong Long, Rui He, Huanhuan Lyu, Lin Chen, Yihui Wen
Формат: Статья
Язык:English
Опубликовано: BMC 2024-10-01
Серии:Head & Face Medicine
Предметы:
Amphiregulin
Epidermal growth factor receptor
Laryngeal squamous cell carcinoma
Immunosuppressive microenvironment
Regulatory T cells
Online-ссылка:https://doi.org/10.1186/s13005-024-00466-6

Internet

https://doi.org/10.1186/s13005-024-00466-6

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