Elevated phospholipids and acylcarnitines C4 and C5 in cerebrospinal fluid distinguish viral CNS infections from autoimmune neuroinflammation

Elevated phospholipids and acylcarnitines C4 and C5 in cerebrospinal fluid distinguish viral CNS infections from autoimmune neuroinflammation

Abstract Background Viral and autoimmune encephalitis may present with similar symptoms, but require different treatments. Thus, there is a need for biomarkers to improve diagnosis and understanding of pathogenesis. We hypothesized that virus-host cell interactions lead to different changes in centr...

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Bibliographic Details
Main Authors: Amani Al-Mekhlafi, Fakhar H. Waqas, Maike Krueger, Frank Klawonn, Manas K. Akmatov, Kirsten Müller-Vahl, Corinna Trebst, Thomas Skripuletz, Martin Stangel, Kurt-Wolfram Sühs, Frank Pessler
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Autoimmunity
Biomarkers
Cell membrane
Central nervous system
Fatty acid oxidation
Encephalitis
Online Access:https://doi.org/10.1186/s12967-023-04637-y

Internet

https://doi.org/10.1186/s12967-023-04637-y

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