Korean Red Ginseng Improves Astrocytic Mitochondrial Function by Upregulating HO-1-Mediated AMPKα–PGC-1α–ERRα Circuit after Traumatic Brain Injury

Korean Red Ginseng Improves Astrocytic Mitochondrial Function by Upregulating HO-1-Mediated AMPKα–PGC-1α–ERRα Circuit after Traumatic Brain Injury

Heme oxygenase-1 (HO-1) exerts beneficial effects, including angiogenesis and energy metabolism via the peroxisome proliferator-activating receptor-γ coactivator-1α (PGC-1α)–estrogen-related receptor α (ERRα) pathway in astrocytes. However, the role of Korean red ginseng extract (KRGE) in HO-1-media...

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Bibliographic Details
Main Authors: Minsu Kim, Joohwan Kim, Sunhong Moon, Bo Young Choi, Sueun Kim, Hui Su Jeon, Sang Won Suh, Young-Myeong Kim, Yoon Kyung Choi
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
Korean red ginseng
heme oxygenase-1
traumatic brain injury
AMPKα–PGC-1α–ERRα circuit
astrocytic mitochondrial function
Online Access:https://www.mdpi.com/1422-0067/22/23/13081

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https://www.mdpi.com/1422-0067/22/23/13081

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