Bacterial Argonaute Proteins Aid Cell Division in the Presence of Topoisomerase Inhibitors in Escherichia coli

Bacterial Argonaute Proteins Aid Cell Division in the Presence of Topoisomerase Inhibitors in Escherichia coli

ABSTRACT Prokaryotic Argonaute (pAgo) proteins are guide-dependent nucleases that function in host defense against invaders. Recently, it was shown that TtAgo from Thermus thermophilus also participates in the completion of DNA replication by decatenating chromosomal DNA. Here, we show that two pAgo...

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Bibliographic Details
Main Authors: Anna Olina, Aleksei Agapov, Denis Yudin, Dmitry Sutormin, Alina Galivondzhyan, Anton Kuzmenko, Konstantin Severinov, Alexei A. Aravin, Andrey Kulbachinskiy
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
prokaryotic Argonautes
gyrase
DNA replication
ter sites
cell division
DNA gyrase
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04146-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04146-22

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