Association between urinary biomarkers MMP-7/TIMP-2 and reduced renal function in children with ureteropelvic junction obstruction.

Association between urinary biomarkers MMP-7/TIMP-2 and reduced renal function in children with ureteropelvic junction obstruction.

<h4>Importance</h4>Extracellular matrix proteins and enzymes involved in degradation have been found to be associated with tissue fibrosis and ureteropelvic junction obstruction (UPJO). In this study we developed a promising urinary biomarker model which can identify reduced renal functi...

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Bibliographic Details
Main Authors: Hsin-Hsiao S Wang, Patricia S Cho, Hui Zhi, Stephen A Kostel, Shannon DiMartino, Adelle M Dagher, Kylie H Davis, Lily D Cabour, Ashley Shimmel, James Lee, John W Froehlich, David Zurakowski, Marsha A Moses, Richard S Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0270018

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https://doi.org/10.1371/journal.pone.0270018

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