Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA‐DRB1 Genotype Associations and Immunological and Clinical Manifestations

Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA‐DRB1 Genotype Associations and Immunological and Clinical Manifestations

Objective The heterogeneity of systemic lupus erythematosus (SLE) constitutes clinical and therapeutical challenges. We therefore studied whether unrecognized disease subgroups can be identified by using autoantibody profiling together with HLA‐DRB1 alleles and immunological and clinical data. Metho...

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Bibliographic Details
Main Authors: Lina‐Marcela Diaz‐Gallo, Vilija Oke, Emeli Lundström, Kerstin Elvin, Yee Ling Wu, Susanna Eketjäll, Agneta Zickert, Johanna T. Gustafsson, Andreas Jönsen, Dag Leonard, Daniel J. Birmingham, Gunnel Nordmark, Anders A. Bengtsson, Lars Rönnblom, Iva Gunnarsson, Chack‐Yung Yu, Leonid Padyukov, Elisabet Svenungsson
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:ACR Open Rheumatology
Online Access:https://doi.org/10.1002/acr2.11343

Internet

https://doi.org/10.1002/acr2.11343

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