Polyhydroxybutyrate targets mammalian mitochondria and increases permeability of plasmalemmal and mitochondrial membranes.

Polyhydroxybutyrate targets mammalian mitochondria and increases permeability of plasmalemmal and mitochondrial membranes.

Poly(3-hydroxybutyrate) (PHB) is a polyester of 3-hydroxybutyric acid (HB) that is ubiquitously present in all organisms. In higher eukaryotes PHB is found in the length of 10 to 100 HB units and can be present in free form as well as in association with proteins and inorganic polyphosphate. It has...

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Bibliographic Details
Main Authors: Pia A Elustondo, Plamena R Angelova, Michał Kawalec, Michał Michalak, Piotr Kurcok, Andrey Y Abramov, Evgeny V Pavlov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781052?pdf=render

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http://europepmc.org/articles/PMC3781052?pdf=render

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