Combining a Pharmacological Network Model with a Bayesian Signal Detection Algorithm to Improve the Detection of Adverse Drug Events

Combining a Pharmacological Network Model with a Bayesian Signal Detection Algorithm to Improve the Detection of Adverse Drug Events

Introduction: Improving adverse drug event (ADE) detection is important for post-marketing drug safety surveillance. Existing statistical approaches can be further optimized owing to their high efficiency and low cost.Objective: The objective of this study was to evaluate the proposed approach for u...

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Bibliographic Details
Main Authors: Xiangmin Ji, Guimei Cui, Chengzhen Xu, Jie Hou, Yunfei Zhang, Yan Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
adverse drug events
pharmacological network model
signal detection algorithm
FDA adverse event reporting system
pharmacovigilance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.773135/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.773135/full

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