LncRNA MSTRG.22719.16 mediates the reduction of enoxaparin sodium high-viscosity bone cement-induced thrombosis by targeting the ocu-miR-326-5p/CD40 axis

LncRNA MSTRG.22719.16 mediates the reduction of enoxaparin sodium high-viscosity bone cement-induced thrombosis by targeting the ocu-miR-326-5p/CD40 axis

Abstract Objective Polymethylmethacrylate (PMMA) bone cement promotes the development of local thrombi. Our study found that a novel material, ES-PMMA bone cement, can reduce local thrombosis. We used a simple and reproducible animal model to confirm the reduction in local thrombosis and explored th...

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Bibliographic Details
Main Authors: Linchao Sang, Luobin Ding, Kangning Hao, Ce Zhang, Xiaoyu Shen, Hui Sun, Dehao Fu, Xiangbei Qi
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Thrombosis
Enoxaparin sodium
Endothelial cells
High-throughput RNA sequencing
CeRNA
Online Access:https://doi.org/10.1186/s13018-023-04109-5

Internet

https://doi.org/10.1186/s13018-023-04109-5

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