Computational study and in vitro evaluation of the anti-proliferative activity of novel naproxen derivatives

Computational study and in vitro evaluation of the anti-proliferative activity of novel naproxen derivatives

In the present work, five naproxen derivatives, i.e., 3-amino-(4E)-5-imino-1-[2-(6-methoxy-2-naphthyl)propanoyl]-4-(benzylidene)-4,5-dihydro-1H-pyrazole (a), 3-amino-(4E)-5-imino-1-[2-(6-methoxy-2-naphthyl)propanoyl]-4-(4-bromobenzylidene)-4,5-dihydro-1H-pyrazole (b), 3-amino-(4E)-5-imino-1-[2-(6-me...

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Bibliographic Details
Main Authors: Abdullah G. Al-Sehemi, Ahmad Irfan, Mohammad Alfaifi, Ahmed M. Fouda, Tarek Ma'mon El-Gogary, Diaa A. Ibrahim
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Journal of King Saud University: Science
Subjects:
Biological active compounds
Naproxen derivatives
Quantitative structure–activity relationship
Electro-optical properties
Antiproliferative activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364716304943

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http://www.sciencedirect.com/science/article/pii/S1018364716304943

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