Effects of subchronic fluoride exposure through drinking water on renal toxicity and the expressions of STIM1 and ORAI1 in renal tissues in mice

Effects of subchronic fluoride exposure through drinking water on renal toxicity and the expressions of STIM1 and ORAI1 in renal tissues in mice

BackgroundIt has been found that fluoride may cause cell damage by inducing intracellular calcium overload. Store-operated calcium entry (SOCE) plays an important role in maintaining intracellular calcium homeostasis, but the effect of fluoride on renal SOCE is unknown.ObjectiveTo explore the renal...

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Bibliographic Details
Main Authors: Xuan WU, Fan DING, Yingying LIU, Qing WU
Format: Article
Language:English
Published: Editorial Committee of Journal of Environmental and Occupational Medicine 2022-05-01
Series:环境与职业医学
Subjects:
fluoride
subchronic exposure
nephrotoxicity
store-operated calcium entry
stromal interaction molecule 1
calcium release-activated calcium modulator 1
Online Access:http://www.jeom.org/article/cn/10.11836/JEOM21430

Internet

http://www.jeom.org/article/cn/10.11836/JEOM21430

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