GluN2B and GluN2A-containing NMDAR are differentially involved in extinction memory destabilization and restabilization during reconsolidation

Abstract Extinction memory destabilized by recall is restabilized through mTOR-dependent reconsolidation in the hippocampus, but the upstream pathways controlling these processes remain unknown. Hippocampal NMDARs drive local protein synthesis via mTOR signaling and may control active memory mainten...

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Bibliographic Details
Main Authors: Andressa Radiske, Maria Carolina Gonzalez, Diana A. Nôga, Janine I. Rossato, Lia R. M. Bevilaqua, Martín Cammarota
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80674-7