Machine Learning Prediction of Adenovirus D8 Conjunctivitis Complications from Viral Whole-Genome Sequence

Machine Learning Prediction of Adenovirus D8 Conjunctivitis Complications from Viral Whole-Genome Sequence

Objective: To obtain complete DNA sequences of adenoviral (AdV) D8 genome from patients with conjunctivitis and determine the relation of sequence variation to clinical outcomes. Design: This study is a post hoc analysis of banked conjunctival swab samples from the BAYnovation Study, a previously co...

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Main Authors: Kenji Nakamichi, Lakshmi Akileswaran, PhD, Thomas Meirick, MD, Michele D. Lee, MD, James Chodosh, MD, Jaya Rajaiya, PhD, David Stroman, PhD, Alejandro Wolf-Yadlin, PhD, Quinn Jackson, W. Bradley Holtz, Aaron Y. Lee, MD, Cecilia S. Lee, MD, Russell N. Van Gelder, MD, PhD, Gregg J. Berdy, James D. Branch, El-Roy Dixon, Sherif M. El-Harazi, Jack V. Greiner, Joshua Herz, Larry L. Lothringer, Damien Macaluso, Andrew L. Moyes, George Nardin, Bernard R. Perez, Lawerence E. Roel, Syamala H.K. Reddy, Stephanie Becker, Neil Shmunes, Stephen Smith, Michael Tepedino, Jonathan Macy, Prashant Garg, Nivedita Patil, Yasmin Bhagat, Malavika Krishnaswamy, Nagappa Somshekhar, Manisha Acharya, Shree Kumar Reddy, Mary Abraham, Shobha Kini, Nita Shanbag, P.N. Biswas, Virendra Agarwal, Anshu Sahai, P.S. Girija Devi, Vupputuri Venkata Lakshmi, Narasimha Rao, Radhika Tandon, Priti Kapadia, Deepak Mehta, Anju Kochar, Adriana dos Santos Forseto, Rubens Belfort, Jr., Jacob Moyses Cohen, Ramon Coral Ghanem, Roberta De Ventura, Sergio Luis Gianotti Pimentel, Sergio Kwitko, Maria Cristina Nishiwaki Dantas, Anna Maria Hofling-Lima, Walton Nose, D. Wariyapola, M. Wijetunge, Charith Fonseka, Champa Banagala, K.A. Salvin, D.R. Kodikara
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Ophthalmology Science
Subjects:
Adenovirus D8
Conjunctivitis
Machine learning
Subepithelial infiltrates
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914522000550

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http://www.sciencedirect.com/science/article/pii/S2666914522000550

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