Prophylactic intravitreal 5-fluorouracil and heparin to prevent proliferative vitreoretinopathy in high-risk patients with retinal detachment: study protocol for a randomized controlled trial

Prophylactic intravitreal 5-fluorouracil and heparin to prevent proliferative vitreoretinopathy in high-risk patients with retinal detachment: study protocol for a randomized controlled trial

Abstract Background Proliferative vitreoretinopathy (PVR) is the major cause for postoperative failure after vitreo-retinal surgery for primary rhegmatogenous retinal detachment (RRD). Adjunct pharmaceutical therapy was found to be ineffective once PVR is established. Preliminary data suggest that p...

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Bibliographic Details
Main Authors: Friederike Schaub, Robert Hoerster, Petra Schiller, Moritz Felsch, Daria Kraus, Marouan Zarrouk, Bernd Kirchhof, Sascha Fauser
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Trials
Subjects:
Proliferative vitreoretinopathy
Retinal detachment
Complication
5-Fluorouracil
Heparin
Placebo
Online Access:http://link.springer.com/article/10.1186/s13063-018-2761-x

Internet

http://link.springer.com/article/10.1186/s13063-018-2761-x

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