May the Odds Be Ever in Your Favor: Non-deterministic Mechanisms Diversifying Cell Surface Molecule Expression

May the Odds Be Ever in Your Favor: Non-deterministic Mechanisms Diversifying Cell Surface Molecule Expression

How does the information in the genome program the functions of the wide variety of cells in the body? While the development of biological organisms appears to follow an explicit set of genomic instructions to generate the same outcome each time, many biological mechanisms harness molecular noise to...

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Bibliographic Details
Main Authors: Donnell L. Williams, Veronica Maria Sikora, Max A. Hammer, Sayali Amin, Taema Brinjikji, Emily K. Brumley, Connor J. Burrows, Paola Michelle Carrillo, Kirin Cromer, Summer J. Edwards, Olivia Emri, Daniel Fergle, M. Jamal Jenkins, Krishangi Kaushik, Daniella D. Maydan, Wrenn Woodard, E. Josephine Clowney
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
monogenic
monoallelic
stochastic gene choice
V(D)J recombination
Dscam
protocadherin
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.720798/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.720798/full

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