Variant HNF1 Modulates Epithelial Plasticity of Normal and Transformed Ovary Cells

Variant HNF1 Modulates Epithelial Plasticity of Normal and Transformed Ovary Cells

Ovarian carcinoma arises from the ovarian surface epithelium, which undergoes phenotypic changes characteristic of müllerian epithelium during the first stages of tumorigenesis. The variant isoform of the hepatocyte nuclear factor 1 (vHNF1) is a transcription factor involved in the development of ti...

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Bibliographic Details
Main Authors: Antonella Tomassetti, Giuseppina De Santis, Giancarlo Castellano, Silvia Miotti, Mimma Mazzi, Daniela Tomasoni, Frans Van Roy, Maria Luisa Carcangiu, Silvana Canevari
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608800929

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http://www.sciencedirect.com/science/article/pii/S1476558608800929

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