Functions of exogenous FGF signals in regulation of fibroblast to myofibroblast differentiation and extracellular matrix protein expression

Fibroblasts are widely distributed cells found in most tissues and upon tissue injury, they are able to differentiate into myofibroblasts, which express abundant extracellular matrix (ECM) proteins. Overexpression and unordered organization of ECM proteins cause tissue fibrosis in damaged tissue. Fi...

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Bibliographic Details
Main Authors: Changye Sun, Xiangqin Tian, Yangyang Jia, Mingming Yang, Yong Li, David G. Fernig
Format: Article
Language:English
Published: The Royal Society 2022-09-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.210356