Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis

Glycyrrhetinic acid inhibits non-small cell lung cancer via promotion of Prdx6- and caspase-3-mediated mitochondrial apoptosis

Glycyrrhetinic acid (GA) shows great efficiency against non-small cell lung cancer (NSCLC), but the detailed mechanism is unclear, which has limited its clinical application. Herein, we investigated the potential targets of GA against NSCLC by activity-based protein profiling (ABPP) technology and t...

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Bibliographic Details
Main Authors: Qiuyan Guo, Minghong Zhao, Qixin Wang, Tianming Lu, Piao Luo, Lin Chen, Fei Xia, Huanhuan Pang, Shengnan Shen, Guangqing Cheng, Chuanhao Dai, Yuqing Meng, Tianyu Zhong, Chong Qiu, Jigang Wang
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Glycyrrhetinic acid
NSCLC
Activity-based protein profiling
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224001859

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http://www.sciencedirect.com/science/article/pii/S0753332224001859

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