SuperGAG biopolymers for treatment of excessive bladder permeability

Abstract Few therapeutic options exist for treatment of IC/BPS. A novel high MW GAG biopolymer (“SuperGAG”) was synthesized by controlled oligomerization of CS, purified by TFF and characterized by SEC‐MALLS and 1H‐NMR spectroscopy. The modified GAG biopolymer was tested in an OVX female rat model i...

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Bibliographic Details
Main Authors: Rheal A. Towner, Beverley Greenwood‐Van Meerveld, Ehsan Mohammadi, Debra Saunders, Nataliya Smith, Grannum R. Sant, Harrison C. Shain, Thomas H. Jozefiak, Robert E. Hurst
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.709