NETosis in Long-Term Type 1 Diabetes Mellitus and Its Link to Coronary Artery Disease

BackgroundNeutrophil extracellular traps NETs have been linked to glucose and the pathogenesis of type 1 diabetes mellitus (T1DM). NETs also play a role in vascular inflammation and the development of coronary artery disease (CAD). The role of NETs in CAD progression in patients with long-term T1DM...

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Bibliographic Details
Main Authors: Sverre Grøver Aukrust, Kristine Bech Holte, Trine B. Opstad, Ingebjørg Seljeflot, Tore Julsrud Berg, Ragnhild Helseth
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.799539/full