TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers.

Lung cancer is the leading cause of cancer deaths worldwide; survival times are poor despite therapy. The role of the two-pore domain K+ (K2P) channel TASK-1 (KCNK3) in lung cancer is at present unknown. We found that TASK-1 is expressed in non-small cell lung cancer (NSCLC) cell lines at variable l...

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Bibliographic Details
Main Authors: Katharina Leithner, Birgit Hirschmugl, Yingji Li, Bi Tang, Rita Papp, Chandran Nagaraj, Elvira Stacher, Philipp Stiegler, Jörg Lindenmann, Andrea Olschewski, Horst Olschewski, Andelko Hrzenjak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4905626?pdf=render