Topical Delivery of Diacetyl Boldine in a Microemulsion Formulation for Chemoprotection against Melanoma

Topical Delivery of Diacetyl Boldine in a Microemulsion Formulation for Chemoprotection against Melanoma

This study aimed to develop a microemulsion formulation for topical delivery of Diacetyl Boldine (DAB) and to evaluate its cytotoxicity against melanoma cell line (B16BL6) in vitro. Using a pseudo-ternary phase diagram, the optimal microemulsion formulation region was identified, and its particle si...

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Bibliographic Details
Main Authors: Ahmed Al Saqr, Manjusha Annaji, Ishwor Poudel, Mohammed F. Aldawsari, Hamad Alrbyawi, Nur Mita, Muralikrishnan Dhanasekaran, Sai H. S. Boddu, Rabin Neupane, Amit K. Tiwari, R. Jayachandra Babu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceutics
Subjects:
diacetyl boldine
melanoma
microemulsion
Online Access:https://www.mdpi.com/1999-4923/15/3/901

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https://www.mdpi.com/1999-4923/15/3/901

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