Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice

Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice

Summary: HIF1-alpha expression defines metabolic compartments in the developing heart, promoting glycolytic program in the compact myocardium and mitochondrial enrichment in the trabeculae. Nonetheless, its role in cardiogenesis is debated. To assess the importance of HIF1-alpha during heart develop...

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Bibliographic Details
Main Authors: Ivan Menendez-Montes, Beatriz Escobar, Manuel J. Gomez, Teresa Albendea-Gomez, Beatriz Palacios, Elena Bonzon-Kulichenko, Jose Luis Izquierdo-Garcia, Ana Vanessa Alonso, Alessia Ferrarini, Luis Jesus Jimenez-Borreguero, Jesus Ruiz-Cabello, Jesus Vázquez, Silvia Martin-Puig
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:iScience
Subjects:
Animal Physiology
Biological Sciences
Cellular Physiology
Developmental Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221000924

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http://www.sciencedirect.com/science/article/pii/S2589004221000924

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