Mutations of Francisella novicida that alter the mechanism of its phagocytosis by murine macrophages.

Infection with the bacterial pathogen Francisella tularensis tularensis (F. tularensis) causes tularemia, a serious and debilitating disease. Francisella tularensis novicida strain U112 (abbreviated F. novicida), which is closely related to F. tularensis, is pathogenic for mice but not for man, maki...

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Bibliographic Details
Main Authors: Xin-He Lai, Renee L Shirley, Lidia Crosa, Duangjit Kanistanon, Rebecca Tempel, Robert K Ernst, Larry A Gallagher, Colin Manoil, Fred Heffron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2912274?pdf=render