Risk stratification based on DNA damage-repair-related signature reflects the microenvironmental feature, metabolic status and therapeutic response of breast cancer

Risk stratification based on DNA damage-repair-related signature reflects the microenvironmental feature, metabolic status and therapeutic response of breast cancer

DNA damage-repair machinery participates in maintaining genomic integrity and affects tumorigenesis. Molecular signatures based on DNA damage-repair-related genes (DRGs) capable of comprehensively indicating the prognosis, tumor immunometabolic profile and therapeutic responsiveness of breast cancer...

Full description

Bibliographic Details
Main Authors: Chunzhen Li, Shu Yu, Jie Chen, Qianshan Hou, Siyi Wang, Cheng Qian, Shulei Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
DNA damage
DNA repair
prognostic signature
immune microenvironment
metabolic status
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1127982/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1127982/full

Similar Items