A bistable gene switch for antibiotic biosynthesis: the butyrolactone regulon in Streptomyces coelicolor.

Many microorganisms, including bacteria of the class Streptomycetes, produce various secondary metabolites including antibiotics to gain a competitive advantage in their natural habitat. The production of these compounds is highly coordinated in a population to expedite accumulation to an effective...

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Bibliographic Details
Main Authors: Sarika Mehra, Salim Charaniya, Eriko Takano, Wei-Shou Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2444045?pdf=render