Genomic landscape and expression profile of consensus molecular subtype four of colorectal cancer

BackgroundCompared to other subtypes, the CMS4 subtype is associated with lacking of effective treatments and poorer survival rates.MethodsA total of 24 patients with CRC were included in this study. DNA and RNA sequencing were performed to acquire somatic mutations and gene expression, respectively...

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Bibliographic Details
Main Authors: Yujie Lu, Dingyi Gu, Chenyi Zhao, Ying Sun, Wenjing Li, Lulu He, Xiaoyan Wang, Zhongyang Kou, Jiang Su, Feng Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1160052/full