Small Molecule Drugs That Inhibit Phagocytosis

Small Molecule Drugs That Inhibit Phagocytosis

In our initial publication on the in vitro testing of more than 200 compounds, we demonstrated that small molecules can inhibit phagocytosis. We therefore theorized that a small molecule drug discovery-based approach to the treatment of immune cytopenias (ITP, AIHA, HTR, DHTR) is feasible. Those ear...

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Bibliographic Details
Main Authors: Melika Loriamini, Melissa M. Lewis-Bakker, Kayluz Frias Boligan, Siming Wang, Mairead B. Holton, Lakshmi P. Kotra, Donald R. Branch
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
immune cytopenias
phagocytosis inhibitors
drug discovery
medicinal chemistry
Online Access:https://www.mdpi.com/1420-3049/28/2/757

Internet

https://www.mdpi.com/1420-3049/28/2/757

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