Photothermia at the nanoscale induces ferroptosis via nanoparticle degradation

Abstract The Fe(II)-induced ferroptotic cell death pathway is an asset in cancer therapy, yet it calls into question the biocompatibility of magnetic nanoparticles. In the latter, Fe(II) is sequestered within the crystal structure and is released only upon nanoparticle degradation, a transition that...

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Bibliographic Details
Main Authors: Alexandre Fromain, Jose Efrain Perez, Aurore Van de Walle, Yoann Lalatonne, Claire Wilhelm
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40258-1